Complete Allergy Chewable Tablets

Pronunciation: DYE-fen-HYE-dra-meen
Generic Name: Diphenhydramine
Brand Name: Examples include Benadryl Allergy and Complete Allergy

Complete Allergy Chewable Tablets are used for:

Preventing or treating symptoms of hay fever, other allergies, and colds, such as stuffy nose, runny nose, sneezing, itching of the nose and throat, coughing, and itchy, watery eyes.

Complete Allergy Chewable Tablets are an antihistamine. It works by blocking the action of histamine, which reduces the symptoms of an allergic reaction.

Do NOT use Complete Allergy Chewable Tablets if:

• you are allergic to any ingredient in Complete Allergy Chewable Tablets


• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Complete Allergy Chewable Tablets:

Some medical conditions may interact with Complete Allergy Chewable Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema, lung disease, shortness of breath, or sleep apnea


• if you have blockage of the stomach, intestine, or urinary tract; difficulty urinating; diabetes; enlargement of the prostate; glaucoma; heart disease; high blood pressure; the blood disease porphyria; or thyroid disease

Some MEDICINES MAY INTERACT with Complete Allergy Chewable Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Complete Allergy Chewable Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Complete Allergy Chewable Tablets:

Use Complete Allergy Chewable Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Complete Allergy Chewable Tablets by mouth with or without food.


• Chew thoroughly before swallowing.


• Use Complete Allergy Chewable Tablets exactly as directed on the package, unless instructed differently by your doctor. If you are taking Complete Allergy Chewable Tablets without a prescription, follow any warnings and precautions on the label.


• If you miss a dose of Complete Allergy Chewable Tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Complete Allergy Chewable Tablets.

Important safety information:

• Complete Allergy Chewable Tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Complete Allergy Chewable Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Complete Allergy Chewable Tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Complete Allergy Chewable Tablets may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.


• Do not become overheated in hot weather or while you are being active; heatstroke may occur.


• Complete Allergy Chewable Tablets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Complete Allergy Chewable Tablets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Complete Allergy Chewable Tablets has diphenhydramine in it. Before you start any new medicine, check the label to see if it has diphenhydramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Do not use Complete Allergy Chewable Tablets for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.


• If your symptoms persist for more than 1 week or if you develop a fever, contact your health care provider.


• Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.


• Use Complete Allergy Chewable Tablets with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness, sedation, and lightheadedness upon standing.


• Complete Allergy Chewable Tablets should not be used in CHILDREN younger than 6 years old without checking with the child's doctor.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Complete Allergy Chewable Tablets while you are pregnant. Complete Allergy Chewable Tablets are found in breast milk. Do not breast-feed while taking Complete Allergy Chewable Tablets.

Possible side effects of Complete Allergy Chewable Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; dry mouth, throat, and nose; thickening of mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; decreased alertness; excitability; fast heartbeat; hallucinations; tightness or pounding in the chest; tremor; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Complete Allergy side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; excitement; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness.

Proper storage of Complete Allergy Chewable Tablets:

Store Complete Allergy Chewable Tablets at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Store in the original package or container. Do not store in the bathroom. Keep Complete Allergy Chewable Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Complete Allergy Chewable Tablets, please talk with your doctor, pharmacist, or other health care provider.


• Complete Allergy Chewable Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Complete Allergy Chewable Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Complete Allergy resources

• Complete Allergy Side Effects (in more detail)
• Complete Allergy Use in Pregnancy & Breastfeeding
• Complete Allergy Drug Interactions
• Complete Allergy Support Group
• 0 Reviews for Complete Allergy - Add your own review/rating

Compare Complete Allergy with other medications

• Allergic Reactions
• Cold Symptoms
• Cough
• Extrapyramidal Reaction
• Hay Fever
• Insomnia
• Motion Sickness
• Nausea/Vomiting
• Pruritus
• Urticaria

Percutaneous Coronary Intervention Medications

Drugs associated with Percutaneous Coronary Intervention

The following drugs and medications are in some way related to, or used in the treatment of Percutaneous Coronary Intervention. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

Topics under Percutaneous Coronary Intervention

• High Risk Percutaneous Transluminal Angioplasty (1 drug)

Drug List:

Angiomax

Integrilin

Plavix

Locapred

Locapred may be available in the countries listed below.

Ingredient matches for Locapred

Desonide

Desonide is reported as an ingredient of Locapred in the following countries:

• Algeria


• Benin


• Burkina Faso


• Cameroon


• Central African Republic


• Chad


• Congo


• Cote D'ivoire


• France


• Gabon


• Guinea


• Luxembourg


• Madagascar


• Mali


• Mauritania


• Niger


• Portugal


• Senegal


• Switzerland


• Togo


• Tunisia


• Zaire

International Drug Name Search

DHEA

In the US, DHEA is a member of the drug class nutraceutical products.

Ingredient matches for DHEA

Dehydroepiandrosterone

Prasterone is reported as an ingredient of DHEA in the following countries:

• Poland

International Drug Name Search

Mianserin Merck NM

Mianserin Merck NM may be available in the countries listed below.

Ingredient matches for Mianserin Merck NM

Mianserin

Mianserin hydrochloride (a derivative of Mianserin) is reported as an ingredient of Mianserin Merck NM in the following countries:

• Denmark

International Drug Name Search

Platinol-AQ

Generic Name: cisplatin (Intravenous route)

sis-PLA-tin

Intravenous route(Powder for Solution)

Administer under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Cumulative renal toxicity associated with cisplatin is severe and other major dose-related toxicities include myelosuppression, nausea, and vomiting. Ototoxicity, which may be more pronounced in children, is significant. Anaphylactic-like reactions to cisplatin such as facial edema, bronchoconstriction, tachycardia, and hypotension have been reported and may occur within minutes of cisplatin administration. Exercise caution to prevent inadvertent cisplatin overdose as doses greater than 100 mg/m(2)/cycle once every 3 to 4 weeks are rarely used. Avoid inadvertent cisplatin overdose due to confusion with carboplatin or prescribing practices that fail to differentiate daily doses from total dose per cycle .

Commonly used brand name(s)

In the U.S.

• Platinol-AQ

Available Dosage Forms:

• Powder for Solution


• Solution

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Platinum Coordination Complex

Uses For Platinol-AQ

Cisplatin belongs to the group of medicines known as alkylating agents. It is used to treat cancer of the bladder, ovaries, and testicles. It may also be used to treat other kinds of cancer, as determined by your doctor.

Cisplatin interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by cisplatin, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with cisplatin, you and your doctor should talk about the good this medicine will do as well as the risks of using it.

Cisplatin is to be administered only by or under the immediate supervision of your doctor.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, cisplatin is used in certain patients with the following medical conditions:

• Cancer of the outside layer of the adrenal gland


• Cancer of the breast


• Cancer of the cervix


• Cancer of the endometrium


• Cancer of the fallopian tube or lining of the abdomen (spreading from the ovary)


• Cancer of the esophagus


• Cancer of the stomach


• Cancer of the lung


• Neuroblastoma (a certain type of cancer in nerve tissues that occurs in children)


• Cancer of the prostate


• Cancers of the head and neck


• Cancer of the liver


• Cancer of the thyroid


• Cancer of the anus


• Cancer of the vulva


• Cancer of the bile duct


• Cancer of the skin, including types that spread to other parts of the body


• Cancer of unknown primary site


• Cancer of the lymph system


• Hepatoblastoma (a certain type of liver cancer that occurs in children)


• Thymoma (a cancer of the thymus, which is a small organ that lies under the breastbone)


• Tumors in the ovaries


• Gestational trophoblastic tumors (tumors in the uterus or womb)


• Wilms' tumor (a cancer of the kidneys occurring mainly in children)


• Retinoblastoma (a cancer of the eye occurring mainly in children)


• Cancer of the bones (in children)


• Cancer of the muscles, connective tissues (tendons), vessels that carry blood or lymph, joints, and fat.


• Autoimmune deficiency syndrome (AIDS)–associated Kaposi's sarcoma (a type of cancer of the skin and mucous membranes that is more common in patients with AIDS)

Before Using Platinol-AQ

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Hearing problems and loss of balance are more likely to occur in children, who are usually more sensitive to the effects of cisplatin.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of cisplatin in the elderly with use in other age groups.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Adenovirus Vaccine Type 4, Live


• Adenovirus Vaccine Type 7, Live


• Bacillus of Calmette and Guerin Vaccine, Live


• Doxorubicin Hydrochloride


• Doxorubicin Hydrochloride Liposome


• Furosemide


• Influenza Virus Vaccine, Live


• Measles Virus Vaccine, Live


• Mumps Virus Vaccine, Live


• Paclitaxel


• Rituximab


• Rotavirus Vaccine, Live


• Rubella Virus Vaccine, Live


• Smallpox Vaccine


• Tacrolimus


• Thioctic Acid


• Topotecan


• Typhoid Vaccine


• Varicella Virus Vaccine


• Vinorelbine


• Yellow Fever Vaccine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Aldesleukin


• Docetaxel


• Fosphenytoin


• Phenytoin


• Tobramycin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Chickenpox (including recent exposure) or


• Herpes zoster (shingles)—Risk of severe disease affecting other parts of the body

• Gout (history of) or


• Kidney stones (history of)—Cisplatin may increase levels of uric acid in the body, which can cause gout or kidney stones

• Hearing problems—May be worsened by cisplatin

• Infection—Cisplatin decreases your body's ability to fight infection

• Kidney disease—Effects of cisplatin may be increased because of slower removal from the body

Proper Use of Platinol-AQ

This medicine is sometimes given together with certain other medicines. If you are using a combination of medicines, it is important that you receive each one at the proper time. If you are taking some of these medicines by mouth, ask your health care professional to help you plan a way to take them at the right times.

While you are receiving this medicine, your doctor may want you to drink extra fluids so that you will pass more urine. This will help prevent kidney problems and keep your kidneys working well.

This medicine usually causes nausea and vomiting that may be severe. However, it is very important that you continue to receive the medicine, even if you begin to feel ill. Ask your health care professional for ways to lessen these effects, especially if they are severe.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Precautions While Using Platinol-AQ

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

While you are being treated with cisplatin, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. Cisplatin may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. In addition, other persons living in your household should not take oral polio vaccine since there is a chance they could pass the polio virus on to you. Also, avoid persons who have taken oral polio vaccine within the last several months. Do not get close to them, and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.

Cisplatin can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

• If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.


• Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in urine or stools; or pinpoint red spots on your skin.


• Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.


• Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.


• Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.


• Avoid contact sports or other situations where bruising or injury could occur.

If cisplatin accidentally seeps out of the vein into which it is injected, it may damage some tissues and cause scarring. Tell the doctor or nurse right away if you notice redness, pain, or swelling at the place of injection.

Platinol-AQ Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Also, because of the way cancer medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Discuss these possible effects with your doctor.

Check with your doctor immediately if any of the following side effects occur:

Less common

• Black, tarry stools


• blood in urine or stools


• cough or hoarseness accompanied by fever or chills


• dizziness or faintness (during or shortly after a dose)


• fast heartbeat (during or shortly after a dose)


• fever or chills


• lower back or side pain accompanied by fever or chills


• painful or difficult urination accompanied by fever or chills


• pain or redness at place of injection


• pinpoint red spots on skin


• swelling of face (during or shortly after a dose)


• unusual bleeding or bruising


• wheezing (during or shortly after a dose)

Check with your doctor as soon as possible if any of the following side effects occur:

More common

• Joint pain


• loss of balance


• ringing in ears


• swelling of feet or lower legs


• trouble in hearing


• unusual tiredness or weakness

Less common

• Convulsions (seizures)


• loss of reflexes


• loss of taste


• numbness or tingling in fingers or toes


• trouble in walking

Rare

• Agitation or confusion


• blurred vision


• change in ability to see colors (especially blue or yellow)


• muscle cramps


• sores in mouth and on lips

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Nausea and vomiting (severe)

Less common

• Loss of appetite

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

• Black, tarry stools


• blood in urine or stools


• convulsions (seizures)


• cough or hoarseness


• decrease in urination


• fever or chills


• loss of balance


• loss of reflexes


• loss of taste


• lower back or side pain


• numbness or tingling in fingers or toes


• painful or difficult urination


• pinpoint red spots on skin


• ringing in ears


• swelling of feet or lower legs


• trouble in hearing


• trouble in walking


• unusual bleeding or bruising

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Platinol-AQ side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Platinol-AQ resources

• Platinol-AQ Side Effects (in more detail)
• Platinol-AQ Use in Pregnancy & Breastfeeding
• Platinol-AQ Drug Interactions
• Platinol-AQ Support Group
• 0 Reviews for Platinol-AQ - Add your own review/rating

• Platinol-AQ Prescribing Information (FDA)


• Platinol-AQ Concise Consumer Information (Cerner Multum)


• Platinol-AQ Monograph (AHFS DI)


• Cisplatin Prescribing Information (FDA)


• Cisplatin Professional Patient Advice (Wolters Kluwer)


• Cisplatin MedFacts Consumer Leaflet (Wolters Kluwer)


• Platinol Prescribing Information (FDA)


• cisplatin Concise Consumer Information (Cerner Multum)

Compare Platinol-AQ with other medications

• Bladder Cancer
• Blood Cell Transplantation
• Bone Marrow Transplantation
• Brain Tumor
• Cervical Cancer
• Neuroblastoma
• Non-Small Cell Lung Cancer
• Osteogenic Sarcoma
• Ovarian Cancer
• Testicular Cancer

Plexion

Generic Name: sulfacetamide sodium and sulfur topical (SUL fa SEET a mide SOE dee um and SUL fur TOP i kal)

Brand Names: Avar Cleanser, Avar Gel, Avar LS Cleanser, Avar-E, Avar-E Emollient, Avar-E Green, Avar-e LS, BP 10-Wash, Clarifoam EF, Clenia Emollient Cream, Clenia Foaming Wash, Plexion , Plexion Cleanser, Plexion Cleansing Cloths, Plexion SCT, Prascion, Prascion Cleanser, Prascion FC Cloths, Prascion RA, Rosac, Rosac Wash, Rosaderm Cleanser, Rosanil Cleanser, Rosula, SE 10-5 SS, Sulfacet-R, Sulfatol C, Sulfatol SS, SulZee Wash, Sumaxin, Sumaxin TS, Sumaxin Wash, Suphera, Topisulf, Zencia Wash, Zetacet

What is Plexion (sulfacetamide sodium and sulfur topical)?

Sulfacetamide sodium and sulfur are antibiotic that fight bacteria.

The combination of sulfacetamide sodium and sulfur topical (for the skin) is used to treat acne, rosacea, and seborrheic dermatitis (a red, flaking skin rash).

Sulfacetamide sodium and sulfur topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Plexion (sulfacetamide sodium and sulfur topical)?

You should not use this medication if you are allergy to sulfa drugs or if you have kidney disease. Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water.

Do not cover the treated skin area unless your doctor has told you to.

Avoid using other medications on the areas you treat with sulfacetamide sodium and sulfur topical unless you doctor tells you to.

What should I discuss with my healthcare provider before using Plexion (sulfacetamide sodium and sulfur topical)?

You should not use this medication if you are allergy to sulfa drugs or if you have kidney disease.

To make sure you can safely use this medication, tell your doctor about all of your medical conditions.

FDA pregnancy category C. It is not known whether sulfacetamide sodium and sulfur topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether sulfacetamide sodium and sulfur topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Plexion (sulfacetamide sodium and sulfur topical)?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Wash your hands before and after applying this medication.

Do not cover the treated skin area unless your doctor has told you to.

Use this medication regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Plexion (sulfacetamide sodium and sulfur topical)?

Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water. Do not use sulfacetamide sodium and sulfur topical on sunburned, windburned, dry, chapped, irritated, or broken skin.

Avoid using other medications on the areas you treat with sulfacetamide sodium and sulfur topical unless you doctor tells you to.

Plexion (sulfacetamide sodium and sulfur topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  new or worsening skin rash;

  
  


• 
  

  joint pain;

  
  


• 
  

  fever; or

  
  


• 
  

  mouth sores.

  
  

Less serious side effects may include redness, warmth, swelling, itching, stinging, burning, or irritation of treated skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Plexion (sulfacetamide sodium and sulfur topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied sulfacetamide sodium and sulfur. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Plexion resources

• Plexion Side Effects (in more detail)
• Plexion Use in Pregnancy & Breastfeeding
• Plexion Drug Interactions
• Plexion Support Group
• 0 Reviews for Plexion - Add your own review/rating

• Plexion Prescribing Information (FDA)


• Avar LS Cleanser MedFacts Consumer Leaflet (Wolters Kluwer)


• Clarifoam EF Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Clarifoam EF Prescribing Information (FDA)


• Plexion Cleansing Cloths MedFacts Consumer Leaflet (Wolters Kluwer)


• Plexion SCT Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Plexion TS Emulsion MedFacts Consumer Leaflet (Wolters Kluwer)


• Prascion Cleanser Prescribing Information (FDA)


• Rosac Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Rosaderm Cleanser Prescribing Information (FDA)


• Rosanil Cleanser Prescribing Information (FDA)


• Rosula Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Rosula Prescribing Information (FDA)


• Rosula Cleanser Emulsion MedFacts Consumer Leaflet (Wolters Kluwer)


• Sumadan MedFacts Consumer Leaflet (Wolters Kluwer)


• Sumadan Wash Prescribing Information (FDA)


• Sumaxin Wash MedFacts Consumer Leaflet (Wolters Kluwer)


• Sumaxin Wash Prescribing Information (FDA)


• Zencia Wash Prescribing Information (FDA)

Compare Plexion with other medications

• Acne
• Rosacea
• Seborrheic Dermatitis

Where can I get more information?

• Your pharmacist can provide more information about sulfacetamide sodium and sulfur topical.

See also: Plexion side effects (in more detail)

Amlodipine Mylan

Amlodipine Mylan may be available in the countries listed below.

Ingredient matches for Amlodipine Mylan

Amlodipine

Amlodipine besilate (a derivative of Amlodipine) is reported as an ingredient of Amlodipine Mylan in the following countries:

• Belgium


• France

International Drug Name Search

plerixafor

Generic Name: plerixafor (pler IX a fore)

Brand Names: Mozobil

What is plerixafor?

Plerixafor works by helping your bone marrow release stem cells into your bloodstream so they can be collected and transplanted back into the body.

Plerixafor is used in people with non-Hodgkin's lymphoma or multiple myeloma.

Plerixafor may also be used for purposes not listed in this medication guide.

What is the most important information I should know about plerixafor?

Do not receive plerixafor without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. You should not receive this medication if you are allergic to plerixafor, or if you have leukemia.

Before receiving plerixafor, tell your doctor if you have kidney disease.

Plerixafor is given as an injection in a hospital or clinic setting. Before receiving plerixafor, you will be given another medication that will help your bone marrow produce stem cells and certain white blood cells that help support your immune system.

To be sure this medication is not causing harmful effects, your blood will need to be tested often.

What should I discuss with my health care provider before receiving plerixafor?

You should not receive this medication if you are allergic to plerixafor, or if you have leukemia.

To make sure you can safely use plerixafor, tell your doctor if you have kidney disease.

FDA pregnancy category D. Do not receive plerixafor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. It is not known whether plerixafor passes into breast milk or if it could harm a nursing baby. You should not breast-feed while receiving this medication.

How is plerixafor given?

Plerixafor is injected under the skin. You will receive this injection in a hospital or clinic setting.

Before receiving plerixafor, you will be given a medication called a granulocyte (GRAN-yoo-loe-site) colony stimulating factor, also called G-CSF. Some examples of a G-CSF are filgrastim (Neupogen), pegfilgrastim (Neulasta), and sargramostim (Leukine).

A G-CSF will cause your bone marrow to produce stem cells and certain white blood cells called granulocytes, which help support your immune system.

Plerixafor works together with the G-CSF by causing stem cells and granulocytes produced in the bone marrow to circulate into your blood stream where they can be collected in blood drawn from your vein.

After your blood is drawn, it will be processed so that the needed stem cells and granulocytes can be separated from other unneeded parts of the blood. These stem cells and granulocytes will then be "transplanted" back into your vein through an IV injection.

To be sure plerixafor is not causing harmful effects, your blood will need to be tested often during your treatment.

What happens if I miss a dose?

Because you will receive plerixafor in a clinical setting, you are not likely to miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include stomach discomfort, severe dizziness, or fainting.

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving plerixafor?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Plerixafor side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your caregivers at once if you have a serious side effect such as:

• 
  

  easy bruising or bleeding, unusual weakness;

  
  


• 
  

  feeling like you might pass out; or

  
  


• 
  

  pain in your upper stomach, spreading to your shoulder or back.

  
  

Less serious side effects may include:

• 
  

  nausea, vomiting;

  
  


• 
  

  diarrhea, constipation;

  
  


• 
  

  dry mouth, numbness in or around your mouth;

  
  


• 
  

  upset stomach, bloating, gas;

  
  


• 
  

  tired feeling, trouble sleeping;

  
  


• 
  

  headache, dizziness;

  
  


• 
  

  joint or muscle pain;

  
  


• 
  

  increased sweating; or

  
  


• 
  

  itching, rash, or other irritation where the medication was injected.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Plerixafor Dosing Information

Usual Adult Dose for non-Hodgkin's Lymphoma:

Treatment with plerixafor should begin after the patient has received G-CSF once daily for four days. Plerixafor should be administered approximately 11 hours prior to initiation of apheresis for up to 4 consecutive days.

The recommended dose of plerixafor is 0.24 mg/kg body weight by subcutaneous (SC) injection.

The patient's actual body weight should be used to calculate the volume of plerixafor to be administered. Each vial delivers 1.2 mL of 20 mg/mL solution, and the volume to be administered to patients should be calculated from the following equation:
0.012 X patient's actual body weight (in kg) = volume to be administered (in mL)

In clinical studies, plerixafor dose has been calculated based on actual body weight in patients up to 175% of ideal body weight. The dose of plerixafor and the treatment of patients weighing more than 175% of ideal body weight have not been investigated.

Based on increasing exposure with increasing body weight, the plerixafor dose should not exceed 40 mg/day.

Daily morning doses of G-CSF 10 micrograms/kg for 4 days should be administered prior to the first evening dose of plerixafor and on each day prior to apheresis.

Usual Adult Dose for Multiple Myeloma:

Treatment with plerixafor should begin after the patient has received G-CSF once daily for four days. Plerixafor should be administered approximately 11 hours prior to initiation of apheresis for up to 4 consecutive days.

The recommended dose of plerixafor is 0.24 mg/kg body weight by subcutaneous (SC) injection.

The patient's actual body weight should be used to calculate the volume of plerixafor to be administered. Each vial delivers 1.2 mL of 20 mg/mL solution, and the volume to be administered to patients should be calculated from the following equation:
0.012 X patient's actual body weight (in kg) = volume to be administered (in mL)

In clinical studies, plerixafor dose has been calculated based on actual body weight in patients up to 175% of ideal body weight. The dose of plerixafor and the treatment of patients weighing more than 175% of ideal body weight have not been investigated.

Based on increasing exposure with increasing body weight, the plerixafor dose should not exceed 40 mg/day.

Daily morning doses of G-CSF 10 micrograms/kg for 4 days should be administered prior to the first evening dose of plerixafor and on each day prior to apheresis.

What other drugs will affect plerixafor?

There may be other drugs that can interact with plerixafor. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More plerixafor resources

• Plerixafor Side Effects (in more detail)
• Plerixafor Use in Pregnancy & Breastfeeding
• Plerixafor Support Group
• 0 Reviews for Plerixafor - Add your own review/rating

• plerixafor Subcutaneous Advanced Consumer (Micromedex) - Includes Dosage Information


• Plerixafor Professional Patient Advice (Wolters Kluwer)


• Plerixafor MedFacts Consumer Leaflet (Wolters Kluwer)


• Mozobil Prescribing Information (FDA)


• Mozobil Consumer Overview

Compare plerixafor with other medications

• Multiple Myeloma
• Non-Hodgkin's Lymphoma

Where can I get more information?

• Your doctor or pharmacist can provide more information about plerixafor.

See also: plerixafor side effects (in more detail)

Chlorostat

Generic Name: chlorhexidine topical (klor HEX i deen TOP i kal)

Brand Names: Betasept, Biopatch, Calgon Vesta, Chlorostat, Chlorostat 4, Dyna-Hex, Hibiclens, PerioChip, Spectrum-4

What is Chlorostat (chlorhexidine topical)?

Chlorhexidine is an antiseptic that fights bacteria.

Chlorhexidine topical (for the skin) is used to clean the skin to prevent infection that may be caused by surgery, injection, or skin injury.

Chlorhexidine topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Chlorostat (chlorhexidine topical)?

You should not use chlorhexidine topical if you are allergic to it.

Ask a doctor or pharmacist if it is safe for you to use chlorhexidine topical if you have any allergies to food, dyes, animals, or medicines.

Avoid getting this medication in your eyes, ears, nose, mouth, rectum, or vagina. Chlorhexidine topical is for use only on the skin.

Stop using the medication and call your doctor if you have a skin reaction such as severe burning, itching, redness, blistering, peeling, swelling, rash, or any other severe irritation.

What should I discuss with my health are provider before using Chlorostat (chlorhexidine topical)?

You should not use chlorhexidine topical if you are allergic to it.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have any allergies to food, dyes, animals, or medicines.

FDA pregnancy category C. It is not known whether chlorhexidine topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether chlorhexidine topical passes into breast milk or if it could harm a nursing baby. Do not breast-feed if you are using this medicine to treat a skin condition in the breast area. Chlorhexidine topical should not be used on a child younger than 2 months old.

How should I use Chlorostat (chlorhexidine topical)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Rinse the skin before applying chlorhexidine topical gel or dressing. Apply only enough to cover the area you are treating.

To use chlorhexidine topical soap, apply only enough to cover the area you are treating. Wash the area gently, then rinse thoroughly with plain water. Avoid using over large areas of skin.

Do not apply this medication to deep cuts, scrapes, or open skin wounds. Chlorhexidine topical can also be harmful if it gets in your eyes, ears, mouth, nose, rectum, or vagina.

Call your doctor if your symptoms do not improve, or if they get worse while using chlorhexidine topical.

Some forms of this medicine are flammable. Do not use while you are smoking, or near high heat or open flame. Store at room temperature away from moisture, heat, and light. Do not freeze. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Chlorostat (chlorhexidine topical)?

Avoid getting this medication in your eyes, ears, nose, mouth, rectum, or vagina. If this does happen, rinse with water. Chlorhexidine topical is for use only on the skin.

Avoid using other medications on the areas you treat with chlorhexidine topical unless you doctor tells you to.

Avoid getting this medication on your clothing or other fabrics. Do not use bleach to wash any fabric exposed to chlorhexidine or the medicine may cause a permanent stain.

Chlorostat (chlorhexidine topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using chlorhexidine topical and call your doctor at once if you have a serious side effect such as:

• 
  

  severe burning, itching, or redness;

  
  


• 
  

  blistering or peeling;

  
  


• 
  

  swelling or severe skin rash; or

  
  


• 
  

  any other severe irritation of treated skin.

  
  

Less serious side effects may occur, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Chlorostat (chlorhexidine topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied chlorhexidine topical. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Chlorostat resources

• Chlorostat Side Effects (in more detail)
• Chlorostat Use in Pregnancy & Breastfeeding
• Chlorostat Support Group
• 0 Reviews for Chlorostat - Add your own review/rating

• Chlorostat Advanced Consumer (Micromedex) - Includes Dosage Information


• Betasept Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Peridex Prescribing Information (FDA)


• Peridex Advanced Consumer (Micromedex) - Includes Dosage Information


• Peridex Solution MedFacts Consumer Leaflet (Wolters Kluwer)


• PerioGard Prescribing Information (FDA)


• Periochip Prescribing Information (FDA)

Compare Chlorostat with other medications

• Gingivitis
• Mucositis
• Periodontitis

Where can I get more information?

• Your pharmacist can provide more information about chlorhexidine topical.

See also: Chlorostat side effects (in more detail)

Fortradol

Fortradol may be available in the countries listed below.

Ingredient matches for Fortradol

Tramadol

Tramadol hydrochloride (a derivative of Tramadol) is reported as an ingredient of Fortradol in the following countries:

• Italy

International Drug Name Search

Cinazin

Cinazin may be available in the countries listed below.

Ingredient matches for Cinazin

Cinnarizine

Cinnarizine is reported as an ingredient of Cinazin in the following countries:

• Bangladesh

International Drug Name Search

Plexion TS

Generic Name: sulfacetamide sodium and sulfur topical (SUL fa SEET a mide SOE dee um and SUL fur TOP i kal)

Brand Names: Avar Cleanser, Avar Gel, Avar LS Cleanser, Avar-E, Avar-E Emollient, Avar-E Green, Avar-e LS, BP 10-Wash, Clarifoam EF, Clenia Emollient Cream, Clenia Foaming Wash, Plexion , Plexion Cleanser, Plexion Cleansing Cloths, Plexion SCT, Prascion, Prascion Cleanser, Prascion FC Cloths, Prascion RA, Rosac, Rosac Wash, Rosaderm Cleanser, Rosanil Cleanser, Rosula, SE 10-5 SS, Sulfacet-R, Sulfatol C, Sulfatol SS, SulZee Wash, Sumaxin, Sumaxin TS, Sumaxin Wash, Suphera, Topisulf, Zencia Wash, Zetacet

What is Plexion TS (sulfacetamide sodium and sulfur topical)?

Sulfacetamide sodium and sulfur are antibiotic that fight bacteria.

The combination of sulfacetamide sodium and sulfur topical (for the skin) is used to treat acne, rosacea, and seborrheic dermatitis (a red, flaking skin rash).

Sulfacetamide sodium and sulfur topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Plexion TS (sulfacetamide sodium and sulfur topical)?

You should not use this medication if you are allergy to sulfa drugs or if you have kidney disease. Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water.

Do not cover the treated skin area unless your doctor has told you to.

Avoid using other medications on the areas you treat with sulfacetamide sodium and sulfur topical unless you doctor tells you to.

What should I discuss with my healthcare provider before using Plexion TS (sulfacetamide sodium and sulfur topical)?

You should not use this medication if you are allergy to sulfa drugs or if you have kidney disease.

To make sure you can safely use this medication, tell your doctor about all of your medical conditions.

FDA pregnancy category C. It is not known whether sulfacetamide sodium and sulfur topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether sulfacetamide sodium and sulfur topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Plexion TS (sulfacetamide sodium and sulfur topical)?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Wash your hands before and after applying this medication.

Do not cover the treated skin area unless your doctor has told you to.

Use this medication regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Plexion TS (sulfacetamide sodium and sulfur topical)?

Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water. Do not use sulfacetamide sodium and sulfur topical on sunburned, windburned, dry, chapped, irritated, or broken skin.

Avoid using other medications on the areas you treat with sulfacetamide sodium and sulfur topical unless you doctor tells you to.

Plexion TS (sulfacetamide sodium and sulfur topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  new or worsening skin rash;

  
  


• 
  

  joint pain;

  
  


• 
  

  fever; or

  
  


• 
  

  mouth sores.

  
  

Less serious side effects may include redness, warmth, swelling, itching, stinging, burning, or irritation of treated skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Plexion TS (sulfacetamide sodium and sulfur topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied sulfacetamide sodium and sulfur. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Plexion TS resources

• Plexion TS Side Effects (in more detail)
• Plexion TS Use in Pregnancy & Breastfeeding
• Plexion TS Drug Interactions
• Plexion TS Support Group
• 0 Reviews for Plexion TS - Add your own review/rating

• Plexion TS Emulsion MedFacts Consumer Leaflet (Wolters Kluwer)


• Avar LS Cleanser MedFacts Consumer Leaflet (Wolters Kluwer)


• Clarifoam EF Prescribing Information (FDA)


• Clarifoam EF Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Plexion Prescribing Information (FDA)


• Plexion Cleansing Cloths MedFacts Consumer Leaflet (Wolters Kluwer)


• Plexion SCT Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Prascion Cleanser Prescribing Information (FDA)


• Rosac Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Rosaderm Cleanser Prescribing Information (FDA)


• Rosanil Cleanser Prescribing Information (FDA)


• Rosula Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Rosula Prescribing Information (FDA)


• Rosula Cleanser Emulsion MedFacts Consumer Leaflet (Wolters Kluwer)


• Sumadan MedFacts Consumer Leaflet (Wolters Kluwer)


• Sumadan Wash Prescribing Information (FDA)


• Sumaxin Wash MedFacts Consumer Leaflet (Wolters Kluwer)


• Sumaxin Wash Prescribing Information (FDA)


• Zencia Wash Prescribing Information (FDA)

Compare Plexion TS with other medications

• Acne
• Rosacea
• Seborrheic Dermatitis

Where can I get more information?

• Your pharmacist can provide more information about sulfacetamide sodium and sulfur topical.

See also: Plexion TS side effects (in more detail)

Plasma-Lyte 56

Dosage Form: Injection

Plasma-Lyte 56 Description

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) is a sterile, nonpyrogenic, hypotonic solution in a single dose container for intravenous administration. Each 100 mL contains 234 mg of Sodium Chloride, USP (NaCl); 128 mg of Potassium Acetate, USP (C2H3KO2); and 32 mg of Magnesium Acetate Tetrahydrate (Mg(C2H3O2)2•4H2O). It contains no antimicrobial agents. The pH is adjusted with hydrochloric acid. The pH is 5.5 (4.0 to 8.0).

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) administered intravenously has value as a source of water and electrolytes. One liter has an ionic concentration of 40 mEq sodium, 13 mEq potassium, 3 mEq magnesium, 40 mEq chloride, and 16 mEq acetate. The osmolarity is 111 mOsmol/L (calc). Normal physiologic osmolarity range is approximately 280 to 310 mOsmol/L. Administration of substantially hypertonic solutions may cause vein damage.

The VIAFLEX plastic container is fabricated from a specially formulated polyvinyl chloride (PL 146 Plastic). The amount of water that can permeate from inside the container into the overwrap is insufficient to affect the solution significantly. Solutions in contact with the plastic container can leach out certain of its chemical components in very small amounts within the expiration period, e.g., di-2-ethylhexyl phthalate (DEHP), up to 5 parts per million. However, the safety of the plastic has been confirmed in tests in animals according to USP biological tests for plastic containers as well as by tissue culture toxicity studies.

Plasma-Lyte 56 - Clinical Pharmacology

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) has value as a source of water and electrolytes. It is capable of inducing diuresis depending on the clinical condition of the patient.

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) produces a metabolic alkalinizing effect. Acetate ions are metabolized ultimately to carbon dioxide and water, which requires the consumption of hydrogen cations.

Indications and Usage for Plasma-Lyte 56

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) is indicated as a source of water and electrolytes or as an alkalinizing agent.

Contraindications

None known

Warnings

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exists edema with sodium retention.

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should be used with great care, if at all, in patients with hyperkalemia, severe renal failure and in conditions in which potassium retention is present.

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should be used with great care in patients with metabolic or respiratory alkalosis. The administration of acetate ions should be done with great care in those conditions in which there is an increased level or an impaired utilization of these ions, such as severe hepatic insufficiency.

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should not be administered simultaneously with blood through the same administration set because of the possibility of hemolysis.

The intravenous administration of Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentrations of the injection. The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentrations of the injection.

In patients with diminished renal function, administration of Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) may result in sodium or potassium retention.

Precautions

Clinical evaluation and periodic laboratory determinations are necessary to monitor changes in fluid balance, electrolyte concentrations and acid base balance during prolonged parenteral therapy or whenever the condition of the patient warrants such evaluation.

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should be used with caution. Excess administration may result in metabolic alkalosis.

Caution must be exercised in the administration of Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) to patients receiving corticosteroids or corticotropin.

Pregnancy

Teratogenic Effects

Pregnancy Category C

Animal reproduction studies have not been conducted with Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP). It is also not known whether Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should be given to a pregnant woman only if clearly needed.

Pediatric Use

Safety and effectiveness of Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) in pediatric patients have not been established by adequate and well controlled trials, however, the use of electrolyte solutions in the pediatric population is referenced in the medical literature. The warnings, precautions and adverse reactions identified in the label copy should be observed in the pediatric population.

Geriatric Use

Clinical studies of Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or drug therapy.

Do not administer unless solution is clear and seal is intact.

Adverse Reactions

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.

Plasma-Lyte 56 Dosage and Administration

As directed by a physician. Dosage is dependent upon the age, weight and clinical condition of the patient as well as laboratory determinations.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

All injections in VIAFLEX plastic containers are intended for intravenous administration using sterile equipment.

Additives may be incompatible. Complete information is not available. Those additives known to be incompatible should not be used. Consult with pharmacist, if available. If, in the informed judgment of the physician, it is deemed advisable to introduce additives, use aseptic technique. Mix thoroughly when additives have been introduced. Do not store solutions containing additives.

How is Plasma-Lyte 56 Supplied

Plasma-Lyte 56 Injection (Multiple Electrolytes Injection, Type 1, USP) in VIAFLEX plastic containers is available as shown below:

Code	Size(mL)	NDC
2B2524	1000	NDC 0338-0168-04

Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. It is recommended the product be stored at room temperature (25°C); brief exposure up to 40°C does not adversely affect the product.

DIRECTIONS FOR USE OF VIAFLEX PLASTIC CONTAINER

Warning: Do not use plastic containers in series connections. Such use could result in air embolism due to residual air being drawn from the primary container before administration of the fluid from the secondary container is completed.

To Open

Tear overwrap down side at slit and remove solution container. Some opacity of the plastic due to moisture absorption during the sterilization process may be observed. This is normal and does not affect the solution quality or safety. The opacity will diminish gradually. Check for minute leaks by squeezing inner bag firmly. If leaks are found, discard solution as sterility may be impaired. If supplemental medication is desired, follow directions below.

Preparation for Administration

1. Suspend container from eyelet support.


2. Remove plastic protector from outlet port at bottom of container.


3. Attach administration set. Refer to complete directions accompanying set.

To Add Medication

Warning: Additives may be incompatible.

To add medication before solution administration

1. Prepare medication site.


2. Using syringe with 19 to 22 gauge needle, puncture resealable medication port and inject.


3. Mix solution and medication thoroughly. For high density medication such as potassium chloride, squeeze ports while ports are upright and mix thoroughly.

To add medication during solution administration

1. Close clamp on the set.


2. Prepare medication site.


3. Using syringe with 19 to 22 gauge needle, puncture resealable medication port and inject.


4. Remove container from IV pole and/or turn to an upright position.


5. Evacuate both ports by squeezing them while container is in the upright position.


6. Mix solution and medication thoroughly.


7. Return container to in use position and continue administration.

Baxter Healthcare Corporation

Deerfield, IL 60015 USA

Printed in USA

*Bar Code Position Only

071942878

07-19-42-878 Rev. February 2004

Baxter, PLASMA-LYTE, VIAFLEX, and PL 146 are

trademarks of Baxter International Inc.

Plasma-Lyte 56  sodium chloride, potassium acetate, magnesium acetate tetrahydrate  injection

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0338-0168 Route of Administration INTRAVENOUS DEA Schedule

INGREDIENTS Name (Active Moiety) Type Strength Sodium Chloride (Sodium Chloride) Active 2.34 MILLIGRAM  In 1 MILLILITER Potassium Acetate (Potassium Acetate) Active 1.28 MILLIGRAM  In 1 MILLILITER Magnesium Acetate Tetrahydrate (Magnesium Acetate Tetrahydrate) Active .23 MILLIGRAM  In 1 MILLILITER Water Inactive

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 0338-0168-04 1000 mL (MILLILITER) In 1 BAG None

Revised: 09/2006Baxter Healthcare Corporation

More Plasma-Lyte 56 resources

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Dimetapp Cold and Fever

Generic Name: acetaminophen, brompheniramine, and pseudoephedrine (a seet a MIN oh fen/brome fen IR a meen/soo doe e FED rin)

Brand Names: Dimetapp Cold and Fever, Dristan Cold Maximum Strength

What is Dimetapp Cold and Fever (acetaminophen, brompheniramine, and pseudoephedrine)?

Acetaminophen is a pain reliever and fever reducer.

Brompheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen, brompheniramine, and pseudoephedrine is used to treat runny or stuffy nose, sinus congestion, sneezing, and pain or fever caused by allergies or the common cold.

Acetaminophen, brompheniramine, and pseudoephedrine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Dimetapp Cold and Fever (acetaminophen, brompheniramine, and pseudoephedrine)?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children. Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Do not take more of this medication than is recommended. An overdose of acetaminophen can cause damage to your liver. Do not use any other over-the-counter cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen, brompheniramine, or pseudoephedrine. Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor's advice, and never take more than 2 grams (2000 mg) per day.

What should I discuss with my healthcare provider before taking Dimetapp Cold and Fever (acetaminophen, brompheniramine, and pseudoephedrine)?

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a decongestant before the MAO inhibitor has cleared from your body. Do not take this medication if you are allergic to acetaminophen, brompheniramine, or pseudoephedrine, or to other antihistamines or decongestants, diet pills, stimulants, or ADHD medications.

Before using acetaminophen, brompheniramine, and pseudoephedrine, tell your doctor if you are allergic to any drugs, or if you have:

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  heart disease or high blood pressure;

  
  


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  liver disease, alcoholism, or cirrhosis of the liver;

  
  


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  glaucoma;

  
  


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  kidney disease;

  
  


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  diabetes;

  
  


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  a thyroid disorder;

  
  


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  an enlarged prostate; or

  
  


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  problems with urination.

  
  

If you have any of these conditions, you may not be able to use this medication, or you may need a dosage adjustment or special tests during treatment.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artifically-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take Dimetapp Cold and Fever (acetaminophen, brompheniramine, and pseudoephedrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine should be taken only for a short time until your symptoms clear up.

Take this medication with food or milk if it upsets your stomach. Drink extra fluids while you are taking acetaminophen, brompheniramine, and pseudoephedrine.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

An overdose of acetaminophen can cause serious harm. The maximum amount of acetaminophen for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more acetaminophen could cause damage to your liver. One acetaminophen, brompheniramine, and pseudoephedrine tablet may contain up to 500 mg of acetaminophen. Know the amount of acetaminophen in the specific product you are taking. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store this medication at room temperature, away from heat, light, and moisture.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of an overdose may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Dimetapp Cold and Fever (acetaminophen, brompheniramine, and pseudoephedrine)?

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. Acetaminophen and pseudoephedrine are contained in many cold and pain medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen or pseudoephedrine. Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor's advice, and never take more than 2 grams (2000 mg) per day. This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Avoid using other medicines that make you sleepy (such as pain medication, muscle relaxers, and medicine to treat depression or anxiety). They can add to sleepiness caused by an antihistamine.

Dimetapp Cold and Fever (acetaminophen, brompheniramine, and pseudoephedrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

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  fast, pounding, or uneven heartbeat;

  
  


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  confusion, hallucinations, unusual thoughts or behavior;

  
  


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  severe dizziness, anxiety, restless feeling, or nervousness;

  
  


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  increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);

  
  


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  urinating less than usual or not at all;

  
  


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  easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

  
  


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  nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  

Keep using the medication and talk with your doctor if you have any of these less serious side effects:

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  blurred vision;

  
  


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  dry mouth;

  
  


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  mild loss of appetite;

  
  


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  nausea, stomach pain, constipation;

  
  


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  dizziness, drowsiness;

  
  


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  problems with memory or concentration;

  
  


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  ringing in your ears;

  
  


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  restless or excitability (especially in children);

  
  


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  sleep problems (insomnia);

  
  


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  skin rash, redness, or itching; or

  
  


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  warmth, tingling, or redness under your skin.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Dimetapp Cold and Fever (acetaminophen, brompheniramine, and pseudoephedrine)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

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  an antidepressant;

  
  


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  a bronchodilator;

  
  


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  a diuretic (water pill);

  
  


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  gout medications;

  
  


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  blood pressure medication;

  
  


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  medication to treat irritable bowel syndrome;

  
  


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  bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol);

  
  


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  seizure medication;

  
  


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  isoniazid;

  
  


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  zidovudine (Retrovir, AZT);

  
  


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  aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others); or

  
  


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  a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), penbutolol (Levatol), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others.

  
  

If you are using any of these drugs, you may not be able to use acetaminophen, brompheniramine, and pseudoephedrine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect acetaminophen, brompheniramine, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Dimetapp Cold and Fever resources

• Dimetapp Cold and Fever Side Effects (in more detail)
• Dimetapp Cold and Fever Use in Pregnancy & Breastfeeding
• Dimetapp Cold and Fever Drug Interactions
• Dimetapp Cold and Fever Support Group
• 0 Reviews for Dimetapp Cold and Fever - Add your own review/rating

Compare Dimetapp Cold and Fever with other medications

• Cold Symptoms
• Hay Fever

Where can I get more information?

• Your pharmacist has information about acetaminophen, brompheniramine, and pseudoephedrine written for health professionals that you may read.

What does my medication look like?

Acetaminophen, brompheniramine, and pseudoephedrine is available over-the-counter (without a prescription) under many brand and generic names. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

See also: Dimetapp Cold and Fever side effects (in more detail)